Ying-hui Chou

Associate Professor, Cognition & Neural Systems
Director, Brain Imaging and Transcranial Magnetic Stimulation (TMS) Laboratory

Research Interests: 

  • Focused primarily on the cognitive and clinical neuroscience of aging and mild cognitive impairment.
  • Particularly interested in integrating brain imaging and transcranial magnetic stimulation (TMS) techniques to develop image-guided therapeutic TMS protocols for memory enhancement.
  • Explore TMS-derived and image-based biomarkers for early diagnosis and prediction of therapeutic outcomes for individuals with mild cognitive impairment and early stages of Alzheimer’s disease.

Updated: 09/05/25

Selected Publications: 

  • Chou, Y.-H., Sundman, M. H., Ton That, V., Green, J., & Trapani, C. (2022). Cortical excitability and plasticity in Alzheimer’s disease and mild cognitive impairment: A systematic review and meta-analysis. Ageing Research Reviewshttps://pubmed.ncbi.nlm.nih.gov/35680080/
  • Sundman, M. H., De Vault, B. E. A., Chen, Y. A., Madhavan, L., Fuglevand, A. J., & Chou, Y.-H. (2023). The (hyper)excitable brain: What can a ubiquitous TMS measure reveal about cognitive aging? Neurobiology of Aging, 132, 250-252. https://pubmed.ncbi.nlm.nih.gov/37827912/
  • Sundman, M. H., Green, J. M., Fuglevand, A. J., & Chou, Y.-H. (2024). TMS-derived short afferent inhibition discriminates cognitive status in older adults without dementia. Aging Brain, 6:100123. https://pubmed.ncbi.nlm.nih.gov/39132326/
  • Hall, J.D., Green, J. M., Chen, A. Y., Liu, Y., Zhang, H., Sundman, M. H., & Chou, Y.-H. (2024). Exploring the potential of combining transcranial magnetic stimulation and electroencephalography to investigate mild cognitive impairment and Alzheimer’s disease: A systematic review. GeroScience, 46, 3659-3693. https://link.springer.com/article/10.1007/s11357-024-01075-6
  • Sundman. M., Lim, K., Ton That, V., Mizell, J.-M., Ugonna, C., Rodriguez, R., Chen, N.-K., Fuglevand, A. J., Liu, Y., Wilson, R. C., Fellous, J.-M., Rapcsak, S., & Chou, Y.-H. (2020). Transcranial magnetic stimulation reveals diminished homeostatic metaplasticity in cognitively impaired adults. Brain Communications, 2, fcaa203. https://pubmed.ncbi.nlm.nih.gov/33376989/
  • Chou, Y.-H., Ton That, V., & Sundman, M. (2020). A systematic review and meta-analysis of rTMS effects on cognitive enhancement in mild cognitive impairment and Alzheimer’s disease. Neurobiology of Aging, 86, 1-10. https://pubmed.ncbi.nlm.nih.gov/31783330/
  • Chen, A. Y., Ton That, V., Ugonna, C., Liu, Y., Nadal, L., & Chou, Y.-H. (2022). Diffusion MRI-guided theta burst stimulation enhances memory and functional connectivity along inferior longitudinal fasciculus in mild cognitive impairment. Proc Natl Acad Sci U S A, 119(21), e2113778119. https://pubmed.ncbi.nlm.nih.gov/35594397/
  • Sundman, M. H., Liu, Y., Chen, N.-K., & Chou, Y.-H. (2025). The glymphatic system as a therapeutic target: TMS-induced modulation in older adults. Frontiers in Aging Neuroscience. https://pmc.ncbi.nlm.nih.gov/articles/PMC12311639/
  • Chou Y.-H., Hickey PT, Sundman M, Song AW, Chen NK. (2015). Effects of Repetitive Transcranial Magnetic Stimulation on Motor Symptoms in Parkinson Disease: A Systematic Review and Meta-analysis. JAMA Neurol, 72(4), 432-40. PMCID: PMC4425190
  • Chou Y.-H, You H, Wang H, Zhao YP, Hou B, Chen NK, Feng F. (2015). Effect of repetitive transcranial magnetic stimulation on fMRI resting-state connectivity in Multiple System Atrophy. Brain Connect, 5(7): 451-9. PMCID: PMC4575511
  • Kielar, A. Patterson, D., & Chou, Y.-H. (2022). Efficacy of repetitive transcranial magnetic stimulation in treating stroke aphasia: Systematic review and meta-analysis. Clinical Neurophysiology, 140, 196-227https://pubmed.ncbi.nlm.nih.gov/35606322/
  • Huskey, A., Fisher, J. M., Hildebrand, L., Negelspach, D. C., Henderson-Arredondo, K., Jankowski, S., Patel, S., Chou, Y.-H., Dailey, N. S., & Killgore, W. D. S. (2024). Polysomnographically mediated cognitive improvements in individuals with insomnia symptoms following continuous theta-burst stimulation of the default mode network. Frontiers in Sleep, section Insomniahttps://www.frontiersin.org/journals/sleep/articles/10.3389/frsle.2024.1424083/full
  • Hildebrand, L., Huskey A., Dailey, N. S., Jankowski, S., Henderson-Arredondo, K., Trapani, C., Patel, S. I., Chen, Y. A., Chou, Y.-H., & Killgore, W. D. S. (2024). Transcranial magnetic stimulation of the default mode network to improve sleep in individuals with insomnia symptoms: A double-blind crossover design. JMIR Research Protocols:13:e51212. https://pubmed.ncbi.nlm.nih.gov/38277210/
  • Kuo, P. H., Chen, Y. A., Rodriguez, R. Stuehm, C., Chalasani, P., Chen, N.-K., & Chou, Y.-H. (2023). Transcranial magnetic stimulation for the treatment of chemo brain. Sensors, 23(19):8017https://pubmed.ncbi.nlm.nih.gov/37836847/

Courses Taught:

  • PSY 300 - Mind & Brain (2024)
  • PSY 321 - Brain Rehabilitation (2024)
  • PSY 422 - Introduction to Brain Connectivity (2022)

*Year listed indicates when this individual last taught the specified course.

Updated: 09/05/25

Degrees

  • Sc.D.