UA Team Tackles Better Brain Health

UA Team Tackles Better Brain Health

A trial will look at whether a naturally occurring compound, known as angiotensin 1-7, relieves cognitive deficits after heart bypass. The UA collaborators include a cardiologist, a physiologist and a psychologist.

Nothing Ventured, Nothing Gained

"We don't know if the drug is going to work in humans," Hay says. "But if we don't do a study like this, we won't know if it will work or not."

But even if it doesn't work, Ryan says, "we're going to have a really strong dataset, and a broad and in-depth analysis of these participants pre- to post-surgery. The whole connection between cardiovascular health and brain health is relatively new, but it's a major focus of the National Heart, Lung and Blood Institute, which funded the study."

Says Sweitzer: "I've never done anything with memory and heart disease. But right after I moved to Arizona, Lee and Meredith came to my office and said, 'We have this compound, and we think it's ready to move into humans, but we don't have any expertise in doing human clinical trial studies.' And that's what I do.

"I think it's a great Arizona story that we had this confluence of expertise across very different and complementary disciplines. This isn't one of those situations where if we don't hurry somebody else will do this. Nobody else can do this. We have this unique combination of expertise right here in Tucson."

Read the article at UA News:
https://uanews.arizona.edu/story/ua-team-tackles-better-brain-health?utm_source=uanow&utm_medium=email&utm_campaign=

(Photos: Bob Demers/UANews)

Published Date: 
08/30/2017 - 11:14